Tribromsalan

Tribromsalan

SCHEMBL11242287

O=C(Nc1ccc(Br)cc1)c1cc(Br)cc(Br)c1O.O=C(Nc1ccc(Br)cc1)c1cc(Br)ccc1O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.86
MEN1 O00255 2/20 0.86
HTT P42858 2/20 0.86
KMT2A Q03164 2/20 0.86
ALDH1A1 P00352 2/20 0.86
EGFR P00533 1/20 0.86
LMNA P02545 1/20 0.86
ERBB2 P04626 1/20 0.86
CYP1A2 P05177 1/20 0.86
LCK P06239 1/20 0.86
CYP2C9 P11712 1/20 0.86
PTGS1 P23219 1/20 0.86
MAPK1 P28482 1/20 0.86
MAPK14 Q16539 1/20 0.86
HSPD1 P10809 3/20 0.69
HSPE1 P61604 3/20 0.69
PLAU P00749 2/20 0.64
F2 P00734 1/20 0.61
F10 P00742 1/20 0.61
PLAT P00750 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tribromsalan SCHEMBL121315 0.93 MEN1 (1.00) MAPTMEN1HTTKMT2AALDH1A1
Tribromsalan SCHEMBL29392740 0.93 MEN1 (1.00) MAPTMEN1HTTKMT2AALDH1A1
Tribromsalan SCHEMBL9526059 0.91 MAPT (0.97) MAPTMEN1HTTKMT2AALDH1A1
Dibromsalan SCHEMBL29496335 0.89 PLAU (0.73) MAPTMEN1HTTKMT2AALDH1A1
Dibromsalan SCHEMBL646973 0.89 PLAU (0.73) MAPTMEN1HTTKMT2AALDH1A1
Tribromsalan SCHEMBL28197430 0.87 HSPD1 (0.80) MAPTMEN1HTTKMT2AALDH1A1
Dibromsalan SCHEMBL29211119 0.84 PLAU (0.66) MAPTMEN1HTTKMT2AALDH1A1
SCHEMBL11679716 0.82 KMT2A (0.80) MAPTMEN1HTTKMT2AALDH1A1
Tribromsalan SCHEMBL29381849 0.82 MAPT (0.79) MAPTMEN1HTTKMT2AALDH1A1
Tribromsalan SCHEMBL28197429 0.82 MEN1 (0.79) MAPTMEN1HTTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4323466-A Germicide LEVER BROTHERS COMPANY (US) 1982-04-06 US disclosed