Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528730 | 0.89 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9525349 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9524583 | 0.75 | KDM4E (0.55) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9525827 | 0.67 | KDM4E (0.48) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9525815 | 0.67 | KDM4E (0.48) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9524667 | 0.67 | KDM4E (0.57) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9524661 | 0.67 | KDM4E (0.57) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL27784404 | 0.67 | BRD4 (0.37) | ALDH1A1BRD4HPGDMAPTTDP1 | |
| SCHEMBL9526250 | 0.65 | KDM4E (0.51) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9526260 | 0.65 | KDM4E (0.51) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |