Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528730 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9525349 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9526075 | 0.75 | ALDH1A1 (0.46) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30250904 | 0.69 | ALOX5 (0.68) | ALOX5ESR1ESR2GABRA1GABRB2 | |
| SCHEMBL5127450 | 0.69 | ALOX5 (0.68) | ALOX5ESR1ESR2GABRA1GABRB2 | |
| SCHEMBL9846336 | 0.68 | GAA (0.51) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8089097 | 0.68 | ALOX5 (0.48) | ALOX5ESR1ESR2GABRA1GABRB2 | |
| SCHEMBL1937421 | 0.67 | KDM4E (0.54) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9525827 | 0.66 | KDM4E (0.48) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9525815 | 0.66 | KDM4E (0.48) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |