Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10513435 | 0.77 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2GLARAB9A | |
| SCHEMBL4457439 | 0.73 | KDM4E (0.42) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 | |
| SCHEMBL10754874 | 0.72 | KDM4E (0.42) | ALDH1A1POLBSMN1; SMN2GLARAB9A | |
| SCHEMBL791644 | 0.70 | — | — | |
| SCHEMBL6535580 | 0.69 | MAPT (0.61) | ALDH1A1POLBSMN1; SMN2GLARAB9A | |
| SCHEMBL27799630 | 0.68 | KDM4E (0.41) | ALDH1A1POLBSMN1; SMN2KDM4EHPGD | |
| SCHEMBL18628562 | 0.67 | MAPT (0.58) | ALDH1A1POLBSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL1156514 | 0.67 | NPC1 (0.47) | ALDH1A1SMN1; SMN2RAB9AKMT2AKDM4E | |
| SCHEMBL28140520 | 0.67 | MAPT (0.40) | ALDH1A1SMN1; SMN2RAB9AKMT2AKDM4E | |
| SCHEMBL20101949 | 0.67 | KMT2A (0.39) | ALDH1A1POLBSMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546082-A1 | HERBICIDAL PYRROLESULFONYLUREAS. | DU PONT (US) | 1993-06-16 | — | — | EP | disclosed |