Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22082710 | 0.76 | MAPK14 (0.48) | SMN1; SMN2GAAACHE | |
| SCHEMBL9526229 | 0.73 | ALDH1A1 (0.46) | KDM4EHPGDSMN1; SMN2ALDH1A1PLA2G10 | |
| SCHEMBL3424232 | 0.72 | MAPT (0.52) | KDM4EHPGDALDH1A1PLA2G10GAA | |
| SCHEMBL7084711 | 0.70 | MAPT (0.45) | KDM4EHPGDSMN1; SMN2ALDH1A1PLA2G10 | |
| SCHEMBL28231027 | 0.70 | ALDH1A1 (0.42) | KDM4EHPGDALDH1A1PLA2G10GAA | |
| SCHEMBL27682990 | 0.70 | CYP2A6 (0.42) | KDM4EHPGDALDH1A1PLA2G10GAA | |
| SCHEMBL57889 | 0.70 | BCL2L1 (0.46) | KDM4EHPGDALDH1A1PLA2G10GAA | |
| SCHEMBL27961010 | 0.70 | KDM4E (0.41) | KDM4EHPGDALDH1A1PLA2G10GAA | |
| SCHEMBL20021713 | 0.70 | KDM4E (0.43) | KDM4EHPGDSMN1; SMN2ALDH1A1PLA2G10 | |
| SCHEMBL9458570 | 0.70 | MDM2 (0.41) | KDM4EHPGDSMN1; SMN2ALDH1A1PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460516-A | Methods and compositions for treating clostridium difficile infection | 马特里瓦克斯公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-116782949-A | Use of short chain fatty acids in cancer prevention | 英联邦高等教育系统天普大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116249689-A | Companion diagnostic tool for reactivating compounds mutating p53 | 皮姆维制药公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-116096704-A | Combination therapy for the treatment of cancer | 皮姆维制药公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2020117075-A1 | ARYLSULFONAMIDES OF 2-ARYLPYRROLE-3-CARBOXAMIDES FOR THE TREATMENT OF CNS DISORDERS | JAGIELLONIAN UNIVERSITY (PL) | 2020-06-11 | — | — | WO | disclosed |
| CN-105986253-B | The plating application and its manufacturing method of excellent adhesion | 阿基里斯株式会社 | 2019-09-27 | — | — | CN | disclosed |
| CN-105524046-B | The method for preparing azole compounds | 武田药品工业株式会社 | 2019-03-29 | — | — | CN | disclosed |
| CN-108129374-A | The method for preparing azole compounds | 武田药品工业株式会社 | 2018-06-08 | — | — | CN | disclosed |
| CN-106659689-A | Inhalable powder formulations of alginate oligomers | 阿尔吉法玛公司 | 2017-05-10 | — | — | CN | disclosed |
| US-20080221151-A1 | 3-AMINO-2-PHENYLPYRROLIDINE DERIVATIVES | HUMPHREY JOHN MICHAEL | 2008-09-11 | — | — | US | disclosed |
| US-20080221151-A1 | 3-AMINO-2-PHENYLPYRROLIDINE DERIVATIVES | HUMPHREY JOHN MICHAEL | 2008-09-11 | — | — | US | disclosed |
| US-7381741-B2 | In which the amino is substituted by arylmethyl- or heteroarylmethyl- group, e.g., 2-Methoxybenzyl)-(2-phenylpyrrolidin-3-yl)-amine and 5-{[2-(3-Chloro-phenyl)-pyrrolidin-3-ylamino]-methyl}-6-methoxy-3-methyl-1,1a,3,7b-tetrahydro-3-aza-cyclopropa[a]naphalen-2-one; neurokinin 1 (Substance P) inhititors | PFIZER INC (US) | 2008-06-03 | — | — | US | disclosed |
| EP-1910454-A1 | TRIETHANOLAMINE PERCHLORATO (TRIFLATO) METAL INNER COMPLEX COORDINATION POLYMERS AS ADDITIVES FOR SYNTHETIC POLYMERS | CATENA Additives GmbH & Co. KG (DE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2006136191-A1 | TRIETHANOLAMINE PERCHLORATO (TRIFLATO) METAL INNER COMPLEX COORDINATION POLYMERS AS ADDITIVES FOR SYNTHETIC POLYMERS | CATENA ADDITIVES GMBH & CO. KG (DE) | 2006-12-28 | — | — | WO | disclosed |
| CN-1067892-A | The preparation method of new pyrrolo-[2,3-b] pyridine derivate | ASTRA AB (SE) | 1993-01-13 | — | — | CN | disclosed |
| EP-0388429-A4 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | — | 1991-08-21 | — | — | EP | disclosed |
| EP-0388429-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-09-26 | — | — | EP | disclosed |
| WO-1989004299-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1989-05-18 | — | — | WO | disclosed |
| EP-0125415-A1 | Process for the production of pyrroles | BASF Aktiengesellschaft (DE) | 1984-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221151-A1 | 3-AMINO-2-PHENYLPYRROLIDINE DERIVATIVES | PBK, KCND3, KCND2 | KDM4E 1394/4885HPGD 935/4885SMN1; SMN2 2785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.