Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCND2 | P30279 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10748221 | 0.81 | SMN1; SMN2 (0.52) | GAALMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8754688 | 0.80 | — | — | |
| SCHEMBL8061638 | 0.77 | LMNA (0.54) | TSHRGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL8061227 | 0.77 | LMNA (0.48) | TSHRGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL6448611 | 0.76 | — | — | |
| SCHEMBL11361526 | 0.76 | MEN1 (0.37) | GAAHTTLMNAMAPTALDH1A1 | |
| SCHEMBL6511999 | 0.73 | KMT2A (0.38) | GAAHTTLMNASMN1; SMN2MAPT | |
| SCHEMBL9021224 | 0.73 | SMN1; SMN2 (0.43) | TSHRGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL9292846 | 0.73 | TSHR (0.41) | TSHRGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL5607162 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251079-B1 | 3-SUBSTITUTED 1-(2-HALOGENOALKOXY-BENZENSULFONYL)-3-HETEROARYLUREA | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-4927454-A | Substituted 1-benzylsulphonyl-3-heteroaryl-(thio)urea herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-22 | — | — | US | disclosed |
| US-4806147-A | Substituted 1-benzylsulphonyl-3-heteroaryl-(thio)urea herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |
| US-4738971-A | ENHANCED CELL-MEDIATED IMMUNITY; ANTIARTHRITIC AGENTS; NONTOXIC | AKTIEBOLASET LEO (SE) | 1988-04-19 | — | — | US | disclosed |
| EP-0251079-A2 | 3-Substituted 1-(2-halogenoalkoxy-benzensulfonyl)-3-heteroarylurea | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |
| EP-0232723-A1 | Herbicidal compositions | BAYER AG (DE) | 1987-08-19 | — | — | EP | disclosed |
| US-4547511-A | FOR ENHANCIN CELL-MEDIATED IMMUNITY | AKTIEBOLAGET LEO (SE) | 1985-10-15 | — | — | US | disclosed |
| EP-0059698-B1 | HETEROCYCLIC CARBOXAMIDES, COMPOSITIONS CONTAINING SUCH COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND METHODS OF TREATMENT THEREWITH | AB LEO (SE) | 1985-09-25 | — | — | EP | disclosed |