Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873383 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBL3MBTL1ALOX15HTT | |
| SCHEMBL10875519 | 0.85 | L3MBTL1 (0.50) | SMN1; SMN2L3MBTL1CYP3A4LIMK2CFTR | |
| SCHEMBL10878001 | 0.83 | ALOX15 (0.43) | SMN1; SMN2POLBALOX15HTTMEN1 | |
| SCHEMBL9525897 | 0.82 | GAA (0.43) | SMN1; SMN2POLBL3MBTL1ALOX15HTT | |
| SCHEMBL10874128 | 0.81 | POLB (0.49) | SMN1; SMN2POLBL3MBTL1ALOX15HTT | |
| SCHEMBL8615545 | 0.80 | LIMK2 (0.63) | L3MBTL1CYP3A4LIMK2MEN1KMT2A | |
| SCHEMBL10875294 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2POLBALOX15HTTLIMK2 | |
| SCHEMBL10875034 | 0.80 | POLB (0.47) | SMN1; SMN2POLBL3MBTL1ALOX15HTT | |
| SCHEMBL10873541 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBALOX15HTTLIMK2 | |
| SCHEMBL6505188 | 0.78 | POLB (0.41) | SMN1; SMN2POLBL3MBTL1ALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |
| EP-0198311-A2 | Nicotin amides and their use as fungicidal agents | F. HOFFMANN-LA ROCHE AG (CH) | 1986-10-22 | — | — | EP | disclosed |