Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10480544 | 0.83 | LMNA (0.41) | KCNH2LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL9522706 | 0.82 | KDM4E (0.39) | KCNH2LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL10480601 | 0.82 | ALDH1A1 (0.44) | KDM4EALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8898775 | 0.81 | KDM4E (0.50) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3239412 | 0.80 | KDM4E (0.48) | KCNH2LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL9664130 | 0.79 | LMNA (0.39) | KCNH2LMNAKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7253434 | 0.79 | KDM4E (0.46) | KCNH2LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL17769247 | 0.78 | LMNA (0.38) | KCNH2LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL9209238 | 0.78 | ALDH1A1 (0.41) | KCNH2LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL10480288 | 0.78 | ALDH1A1 (0.37) | KCNH2LMNAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571400-A1 | NOVEL QUINOLONE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | HANMI PHARMACEUTICAL CO.,LTD. (KR) | 1993-12-01 | — | — | EP | disclosed |