Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27433717 | 0.84 | PTGS1 (0.43) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL575979 | 0.84 | PTGS1 (0.43) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL18126472 | 0.76 | USP2 (0.39) | LMNAUSP2TSHR | |
| SCHEMBL2701823 | 0.75 | APP (0.44) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL28085546 | 0.75 | LMNA (0.36) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL18126342 | 0.74 | USP2 (0.38) | LMNAUSP2TSHR | |
| SCHEMBL6005443 | 0.74 | USP2 (0.33) | LMNAUSP2TSHR | |
| SCHEMBL3219118 | 0.74 | LMNA (0.46) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL20358142 | 0.73 | ATR (0.37) | LMNAUSP2TSHR | |
| SCHEMBL11195053 | 0.72 | LMNA (0.38) | LMNASLC6A6CYP2C19BLMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5025128-A | — | — | None | — | — | JP | disclosed |
| CN-110698358-B | Synthesis of continuous oseltamivir phosphate | 苏州奥普拓新材料有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-110698358-A | Synthesis of continuous oseltamivir phosphate | 苏州奥普拓新材料有限公司 | 2020-01-17 | — | — | CN | disclosed |
| JP-H0525128-A | PRODUCTION OF PYRROLOAZEPINE DERIVATIVE | SUNTORY LTD | 1993-02-02 | — | — | JP | disclosed |