⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527512 | 0.82 | — | — | |
| SCHEMBL9527447 | 0.81 | — | — | |
| SCHEMBL13532584 | 0.78 | — | — | |
| SCHEMBL10766769 | 0.78 | HTR2A (0.38) | — | |
| SCHEMBL9526336 | 0.77 | — | — | |
| SCHEMBL9822816 | 0.77 | — | — | |
| SCHEMBL9823024 | 0.77 | — | — | |
| SCHEMBL9823084 | 0.77 | — | — | |
| SCHEMBL9526543 | 0.76 | — | — | |
| SCHEMBL13532586 | 0.76 | HTR1A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957913-A | N-((4-ARYLPIPERAZINO)ALKYL) SUBSTITTUTED | AMERICAN HOME PRODUCTS CORP. (US) | 1990-09-18 | — | — | US | claimed |
| EP-0220873-B1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PROD (US) | 1993-11-24 | — | — | EP | disclosed |
| US-4957913-A | N-((4-ARYLPIPERAZINO)ALKYL) SUBSTITTUTED | AMERICAN HOME PRODUCTS CORP. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4892943-A | ANTIPSYCHOTIC, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |