Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.69 |
| ▸ | MAOB | P27338 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.58 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901142 | 0.91 | NR4A2 (0.74) | NR4A2MAOBPTPN1SMPD1SRD5A2 | |
| SCHEMBL954459 | 0.85 | NR4A2 (0.66) | NR4A2MAOBPTPN1SMPD1SRD5A2 | |
| SCHEMBL1122713 | 0.83 | NR4A2 (0.94) | NR4A2MAOBSMPD1SRD5A2TSHR | |
| SCHEMBL904248 | 0.83 | CTBP2 (0.60) | MRGPRX4MEN1KMT2A | |
| SCHEMBL30342076 | 0.83 | CTBP2 (0.60) | MRGPRX4MEN1KMT2A | |
| SCHEMBL2790268 | 0.83 | NR4A2 (0.62) | NR4A2MAOBPTPN1SMPD1SRD5A2 | |
| SCHEMBL2848980 | 0.83 | NR4A2 (0.62) | NR4A2MAOBSMPD1SRD5A2TSHR | |
| SCHEMBL670027 | 0.83 | MAOB (0.68) | NR4A2MAOBPTPN1SMPD1SRD5A2 | |
| SCHEMBL14432660 | 0.82 | NR4A2 (0.55) | NR4A2MAOBPTPN1SMPD1SRD5A2 | |
| SCHEMBL4220632 | 0.82 | NR4A1 (0.72) | NR4A2MAOBPTPN1SRD5A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |
| EP-0079168-A1 | Process for making 1-(3-benzyloxyphenyl)-1,1-dimethylheptane and intermediates therefor | PFIZER INC. (US) | 1983-05-18 | — | — | EP | disclosed |
| US-4360700-A | Intermediates for making 1-(3-benzyloxyphenyl)-1,1-dimethylheptane | PFIZER INC. (US) | 1982-11-23 | — | — | US | disclosed |