Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.59 |
| ▸ | CCKAR | P32238 | 9/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526459 | 0.74 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9526467 | 0.74 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9526199 | 0.72 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL16110815 | 0.72 | MEN1 (0.54) | CCKBRCCKARMEN1ALDH1A1KMT2A | |
| SCHEMBL9866963 | 0.72 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9530619 | 0.71 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9524763 | 0.71 | CCKBR (1.00) | CCKBRCCKARMEN1ALDH1A1KMT2A | |
| SCHEMBL9524770 | 0.71 | CCKBR (1.00) | CCKBRCCKARMEN1ALDH1A1KMT2A | |
| SCHEMBL9530610 | 0.71 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9573545 | 0.70 | MEN1 (0.54) | CCKBRCCKARMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167919-B1 | BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1993-05-05 | — | — | EP | claimed |