Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4865869 | 0.82 | LMNA (0.52) | KMT2AMEN1TSHRMAPTALDH1A1 | |
| SCHEMBL676909 | 0.79 | KMT2A (0.58) | MMP2MMP9MMP14KMT2AMEN1 | |
| SCHEMBL9906002 | 0.78 | LMNA (0.54) | KMT2AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6481644 | 0.75 | SLC6A2 (0.51) | KDM1ATSHRMAPTALDH1A1NPC1 | |
| SCHEMBL937164 | 0.75 | SLC6A2 (0.51) | KDM1ATSHRMAPTALDH1A1NPC1 | |
| SCHEMBL2792782 | 0.75 | NPC1 (0.59) | KMT2AMEN1TSHRMAPTALDH1A1 | |
| SCHEMBL14774960 | 0.75 | SMN1; SMN2 (0.50) | MMP2MMP9MMP14KMT2AMEN1 | |
| SCHEMBL9905996 | 0.73 | PRSS1 (0.44) | KMT2AMEN1MAPTALDH1A1HSD17B10 | |
| SCHEMBL14097750 | 0.73 | PRSS1 (0.44) | KMT2AMEN1MAPTALDH1A1HSD17B10 | |
| SCHEMBL13515619 | 0.73 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386451-B1 | OXYGEN-BEARING DIPHENYL HETEROALKANES, PROCESS FOR THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1993-04-28 | — | — | EP | disclosed |
| EP-0386451-A1 | Oxygen-bearing diphenyl heteroalkanes, process for their preparation and use | BASF Aktiengesellschaft (DE) | 1990-09-12 | — | — | EP | disclosed |