SCHEMBL4865869

SCHEMBL4865869

CC(=O)Oc1ccc(C2CO2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
MAPT P10636 4/20 0.47
POLB P06746 2/20 0.47
PKM P14618 1/20 0.47
ELANE P08246 1/20 0.46
GLA P06280 2/20 0.45
HSD17B10 Q99714 3/20 0.44
CUL4A Q13619 1/20 0.44
ESR1 P03372 1/20 0.44
PGR P06401 1/20 0.44
CHRM2 P08172 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
AR P10275 1/20 0.44
CHRM1 P11229 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
ALDH1A1 P00352 3/20 0.43
GAA P10253 2/20 0.43
HSP90AA1 P07900 1/20 0.43
KDM4E B2RXH2 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9526528 0.82 MMP2 (0.43) LMNAMAPTHSD17B10ALDH1A1GAA
SCHEMBL11097182 0.80 LMNA (0.50) LMNAMAPTPOLBPKMELANE
SCHEMBL9906002 0.77 LMNA (0.54) LMNAMAPTPOLBALDH1A1GAA
SCHEMBL4454157 0.77 LMNA (0.55) LMNAMAPTPOLBPKMELANE
SCHEMBL4443112 0.77 LMNA (0.55) LMNAMAPTPOLBPKMELANE
SCHEMBL4454162 0.77 LMNA (0.55) LMNAMAPTPOLBPKMELANE
SCHEMBL4454166 0.77 LMNA (0.55) LMNAMAPTPOLBPKMELANE
SCHEMBL269329 0.77 LMNA (0.80) LMNAMAPTPOLBPKMELANE
SCHEMBL3682712 0.76 PTPN1 (0.44) LMNAMAPTPOLBPKMELANE
SCHEMBL13515619 0.76 KMT2A (0.51) MAPTPOLBELANEGLAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0356070-A1 Synthesis of 4-acetoxystyrene oxide and related compounds HOECHST CELANESE CORPORATION (US) 1990-02-28 EP claimed
JP-2073076-A None JP disclosed
CN-112939883-B Preparation method of polysubstituted 1, 3-oxazolidine compound 兰州大学 2024-01-16 CN disclosed
US-7368219-B2 Polymer for forming anti-reflective coating layer DONGJIN SEMICHEM CO., LTD. (KR) 2008-05-06 US disclosed
US-7368219-B2 Polymer for forming anti-reflective coating layer DONGJIN SEMICHEM CO., LTD. (KR) 2008-05-06 US disclosed
US-7368219-B2 Polymer for forming anti-reflective coating layer DONGJIN SEMICHEM CO., LTD. (KR) 2008-05-06 US disclosed
US-20060134558-A1 Polymer for forming anti-reflective coating layer DONGJIN SEMICHEM CO., LTD. 2006-06-22 US disclosed
US-5466838-A Catalytic reaction of olefin with oxygen in the presence of aldehyde SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-11-14 US disclosed
EP-0540009-B1 Process for producing epoxides SUMITOMO CHEMICAL CO (JP) 1995-08-30 EP disclosed
US-5367087-A Process for producing epoxide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-22 US disclosed
EP-0540009-A1 Process for producing epoxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-05 EP disclosed
EP-0449603-A1 Production of 4-hydroxyphenethyl alcohol HOECHST CELANESE CORPORATION (US) 1991-10-02 EP disclosed
US-5003115-A Epoxidation of acetoxystyrene with a percarboxylic acid to produce acetoxyphenyl oxirane, hydrogenation followed by saponification HOECHST CELANESE CORPORATION (US) 1991-03-26 US disclosed
JP-H0273076-A SYNTHESIS OF 4-ACETOXYSTYRENE OXIDE AND RELATED COMPOUND HOECHST CELANESE CORP 1990-03-13 JP disclosed
EP-0356070-A1 Synthesis of 4-acetoxystyrene oxide and related compounds HOECHST CELANESE CORPORATION (US) 1990-02-28 EP disclosed
EP-0356070-A1 Synthesis of 4-acetoxystyrene oxide and related compounds HOECHST CELANESE CORPORATION (US) 1990-02-28 EP disclosed
EP-0356070-A1 Synthesis of 4-acetoxystyrene oxide and related compounds HOECHST CELANESE CORPORATION (US) 1990-02-28 EP disclosed