Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 11/20 | 1.00 |
| ▸ | CCKBR | P32239 | 7/20 | 1.00 |
| ▸ | CCKAR | P32238 | 4/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526577 | 1.00 | SCN9A (1.00) | SCN9ACCKBRCCKARKCNH2 | |
| SCHEMBL9526582 | 1.00 | SCN9A (1.00) | SCN9ACCKBRCCKARKCNH2 | |
| SCHEMBL6005333 | 0.94 | SCN9A (0.88) | SCN9ACCKBRCCKARKCNH2 | |
| SCHEMBL6005336 | 0.94 | SCN9A (0.88) | SCN9ACCKBRCCKARKCNH2 | |
| SCHEMBL9868387 | 0.92 | CCKBR (1.00) | SCN9ACCKBRCCKARKCNH2 | |
| SCHEMBL9866835 | 0.92 | CCKBR (1.00) | SCN9ACCKBRCCKARKCNH2 | |
| SCHEMBL7066281 | 0.90 | SCN9A (0.82) | SCN9ACCKBRCCKARKCNH2 | |
| SCHEMBL9385707 | 0.90 | SCN9A (0.81) | SCN9ACCKBRCCKARKCNH2 | |
| SCHEMBL7068013 | 0.89 | SCN9A (0.80) | SCN9ACCKBRCCKARKCNH2 | |
| SCHEMBL7312851 | 0.88 | SCN9A (0.79) | SCN9ACCKBRCCKARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167919-B1 | BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1993-05-05 | — | — | EP | claimed |
| EP-0167919-A2 | Benzodiazepine derivatives and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-01-15 | — | — | EP | claimed |
| EP-0167919-B1 | BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |
| US-4820834-A | Benzodiazepine analogs | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0167919-A2 | Benzodiazepine derivatives and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-01-15 | — | — | EP | disclosed |