Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 3/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526579 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9702642 | 0.90 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9702640 | 0.90 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9525396 | 0.90 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9525387 | 0.90 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL7371751 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL7371748 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9701832 | 0.78 | KDM4E (0.77) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9701458 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9701461 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAL3MBTL1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |