Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.42 |
| ▸ | CA2 | P00918 | 14/20 | 0.42 |
| ▸ | CA9 | Q16790 | 8/20 | 0.42 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA6 | P23280 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MMP16 | P51512 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107414 | 0.78 | CA1 (0.41) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL9526615 | 0.75 | CA1 (0.42) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL3284628 | 0.74 | HTR2A (0.48) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL1106519 | 0.74 | CA1 (0.53) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL21826752 | 0.74 | CA2 (0.50) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL30593603 | 0.74 | CA1 (0.53) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL29933194 | 0.74 | CA2 (0.50) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL7351490 | 0.73 | MMP2 (0.60) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL9524316 | 0.73 | CA1 (0.42) | CA1CA2CA9CA5ACA12 | |
| Potassium SCHEMBL9493381 | 0.72 | CA1 (0.51) | CA1CA2CA9CA5ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575378-A1 | BENZENESULFONYLUREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-12-29 | — | — | EP | claimed |
| WO-1992015568-A1 | BENZENESULFONYLUREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-09-17 | — | — | WO | claimed |