Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 17/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526689 | 0.88 | APP (0.42) | APPRORC | |
| SCHEMBL8527197 | 0.87 | RORC (0.53) | RORCDRD2SLC6A4 | |
| SCHEMBL17495376 | 0.82 | RORC (0.70) | RORC | |
| SCHEMBL12129564 | 0.81 | APP (0.77) | APPRORCDRD2SLC6A4 | |
| SCHEMBL17963811 | 0.77 | RORC (0.72) | APPRORC | |
| SCHEMBL12129569 | 0.76 | APP (0.83) | APPRORCDRD2SLC6A4 | |
| SCHEMBL206108 | 0.74 | APP (0.51) | APPRORCDRD2SLC6A4 | |
| SCHEMBL9527227 | 0.74 | APP (0.44) | APPRORCDRD2SLC6A4 | |
| SCHEMBL21384653 | 0.74 | KCNH2 (0.62) | APPDRD2SLC6A4 | |
| SCHEMBL21088053 | 0.74 | APP (0.50) | APPDRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303507-B1 | INDOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 1993-07-28 | — | — | EP | claimed |