Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | RORC | P51449 | 6/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526596 | 0.88 | APP (0.53) | APPRORC | |
| SCHEMBL8316249 | 0.77 | HTR6 (0.53) | HTR6MAPT | |
| SCHEMBL9527801 | 0.76 | HTR6 (0.41) | APPHTR6RORCHTR1AKCNH2 | |
| SCHEMBL8527197 | 0.75 | RORC (0.53) | RORC | |
| SCHEMBL17495392 | 0.72 | RORC (0.76) | RORC | |
| SCHEMBL17495376 | 0.70 | RORC (0.70) | RORC | |
| SCHEMBL8967263 | 0.69 | HTR6 (0.58) | HTR6BRPF1HTR1A | |
| SCHEMBL21088623 | 0.69 | APP (0.59) | APPHTR6RORCHTR1AKCNH2 | |
| SCHEMBL12129564 | 0.68 | APP (0.77) | APPRORCKCNH2 | |
| SCHEMBL7483036 | 0.67 | APP (0.56) | APPHTR6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303507-B1 | INDOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 1993-07-28 | — | — | EP | claimed |