Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | B3GAT3 | O94766 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526819 | 0.96 | CCR2 (0.33) | CCR2B3GAT3ADRA1BMGAMGAA | |
| SCHEMBL9527493 | 0.93 | B3GAT3 (0.33) | CCR2B3GAT3ADRA1BHTR7HTR6 | |
| SCHEMBL9526625 | 0.92 | B3GAT3 (0.33) | CCR2B3GAT3MGAMGAASI | |
| SCHEMBL9528162 | 0.90 | CCR2 (0.35) | CCR2B3GAT3ADRA1BMGAMGAA | |
| SCHEMBL9527486 | 0.89 | B3GAT3 (0.35) | CCR2B3GAT3GPR84 | |
| SCHEMBL9527594 | 0.85 | CCR2 (0.35) | CCR2B3GAT3ADRA1BMGAMGAA | |
| SCHEMBL9526286 | 0.84 | B3GAT3 (0.33) | CCR2B3GAT3HTR7HTR6GPR84 | |
| SCHEMBL9527072 | 0.83 | B3GAT3 (0.34) | CCR2B3GAT3ADRA1BHTR7HTR6 | |
| SCHEMBL9527468 | 0.82 | B3GAT3 (0.35) | CCR2B3GAT3ADRA1BHTR1A | |
| SCHEMBL9527895 | 0.82 | HTR7 (0.34) | CCR2B3GAT3MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337767-B1 | CYCLIC AMIDES | ICI AMERICAS INC. (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0337767-A1 | Cyclic amides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |