Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523933 | 0.88 | MAPT (0.51) | SMN1; SMN2HPGDHTTMAPTNPC1 | |
| SCHEMBL9526419 | 0.85 | MAPT (0.53) | SMN1; SMN2HTTMAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9526790 | 0.84 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTALDH1A1PRMT5 | |
| SCHEMBL9051635 | 0.81 | THRB (0.35) | SMN1; SMN2HPGDHTTALDH1A1GAA | |
| SCHEMBL29384283 | 0.81 | THRB (0.35) | SMN1; SMN2HPGDHTTALDH1A1GAA | |
| SCHEMBL9524791 | 0.79 | NPC1 (0.49) | SMN1; SMN2HTTMAPTNPC1RAB9A | |
| SCHEMBL9525927 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTMAPTNPC1 | |
| SCHEMBL9525001 | 0.78 | NPC1 (0.42) | SMN1; SMN2HPGDHTTMAPTNPC1 | |
| SCHEMBL9524781 | 0.78 | NPC1 (0.38) | SMN1; SMN2HPGDHTTMAPTNPC1 | |
| SCHEMBL9525116 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382380-B1 | PYRIDINIUM NITRATE, ITS PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-4981860-A | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-01-01 | — | — | US | disclosed |
| EP-0382380-A1 | Pyridinium Nitrate, its production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-08-16 | — | — | EP | disclosed |