Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528181 | 0.85 | KMT2A (0.56) | MAOACYP1A2ADRA2ASLC6A2HTR2C | |
| SCHEMBL10381546 | 0.83 | MAOA (0.45) | MAOACYP1A2ADRA2ASLC6A2HTR2C | |
| SCHEMBL9527483 | 0.74 | KMT2A (0.36) | CYP1A2NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL9527201 | 0.73 | KDM4E (0.60) | MAOACYP1A2ADRA2ASLC6A2HTR2C | |
| SCHEMBL22616930 | 0.73 | MAOA (0.86) | MAOAKDM4EKMT2AMTNR1AMTNR1B | |
| 2-Acetylaminofluorene SCHEMBL29829339 | 0.73 | CYP1A2 (1.00) | MAOACYP1A2ADRA2ASLC6A2HTR2C | |
| 2-Acetylaminofluorene SCHEMBL29364009 | 0.73 | CYP1A2 (1.00) | MAOACYP1A2ADRA2ASLC6A2HTR2C | |
| 2-Acetylaminofluorene SCHEMBL21114365 | 0.73 | CYP1A2 (1.00) | MAOACYP1A2ADRA2ASLC6A2HTR2C | |
| 2-Acetylaminofluorene SCHEMBL75140 | 0.73 | CYP1A2 (1.00) | MAOACYP1A2ADRA2ASLC6A2HTR2C | |
| SCHEMBL28178463 | 0.73 | CYP1A2 (0.88) | MAOACYP1A2ADRA2ASLC6A2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |