Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | CA6 | P23280 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527759 | 0.86 | CA1 (0.60) | KDM4EMTNR1AMTNR1BKMT2AMAOA | |
| SCHEMBL14028586 | 0.86 | PARP1 (0.58) | KDM4EMTNR1AMTNR1BKMT2AMAOA | |
| SCHEMBL27715458 | 0.80 | PARP1 (0.76) | MAOACYP1A2ADRA2ASLC6A2HTR2C | |
| SCHEMBL10222677 | 0.80 | BAZ2B (0.57) | KDM4EMTNR1AMTNR1BKMT2AMAOA | |
| SCHEMBL6070648 | 0.79 | MAPK10 (0.55) | KDM4EMTNR1AMTNR1BKMT2AMAOA | |
| SCHEMBL30251048 | 0.76 | CA1 (0.69) | KDM4EKMT2ACA1CA2CA4 | |
| SCHEMBL4627835 | 0.76 | CA1 (0.69) | KDM4EKMT2ACA1CA2CA4 | |
| SCHEMBL7722965 | 0.76 | MTNR1A (1.00) | KDM4EMTNR1AMTNR1BKMT2AMAOA | |
| SCHEMBL31488126 | 0.76 | MTNR1A (1.00) | KDM4EMTNR1AMTNR1BKMT2AMAOA | |
| SCHEMBL8946440 | 0.76 | CA1 (0.63) | CA1CA2CA4CA6CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| WO-1990015800-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |