Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691641 | 0.85 | EPHX1 (0.52) | EPHX1ALDH1A1TSHRPOLBMAPK1 | |
| SCHEMBL8746385 | 0.81 | TSHR (0.67) | EPHX1ALDH1A1TSHRPOLBGAA | |
| SCHEMBL8746369 | 0.80 | EPHX1 (0.53) | EPHX1ALDH1A1TSHRCES1CES2 | |
| SCHEMBL8746368 | 0.80 | EPHX1 (0.53) | EPHX1ALDH1A1TSHRCES1CES2 | |
| SCHEMBL8746372 | 0.80 | EPHX1 (0.53) | EPHX1ALDH1A1TSHRCES1CES2 | |
| SCHEMBL9525910 | 0.79 | TSHR (0.46) | EPHX1ALDH1A1TSHRPOLBGAA | |
| SCHEMBL7112280 | 0.76 | EPHX1 (0.68) | EPHX1ALDH1A1CES1CES2TDP1 | |
| SCHEMBL11693135 | 0.74 | EPHX1 (0.61) | EPHX1ALDH1A1TSHRCES1CES2 | |
| SCHEMBL7405432 | 0.72 | KMT2A (0.58) | ALDH1A1GAAKMT2A | |
| SCHEMBL29897104 | 0.71 | EPHX1 (0.47) | EPHX1ALDH1A1POLBMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153229-B1 | 1-DETHIA 2-THIA-CEPHALOSPORANIC ACID DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS THERAPEUTIC AGENTS AND THE COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-04-07 | — | — | EP | disclosed |
| EP-0153229-A2 | 1-Dethia 2-thia-cephalosporanic acid derivatives, process and intermediates for their preparation, their use as therapeutic agents and the compositions containing them | ROUSSEL-UCLAF (FR) | 1985-08-28 | — | — | EP | disclosed |