Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527149 | 0.85 | EPHX1 (0.49) | EPHX1TSHRKMT2AMEN1POLB | |
| SCHEMBL8746385 | 0.84 | TSHR (0.67) | EPHX1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL9692321 | 0.84 | HIF1A (0.47) | MAPTTSHRKMT2AMEN1POLB | |
| SCHEMBL8746372 | 0.80 | EPHX1 (0.53) | EPHX1TSHRKMT2AMEN1POLB | |
| SCHEMBL8746369 | 0.80 | EPHX1 (0.53) | EPHX1TSHRKMT2AMEN1POLB | |
| SCHEMBL8746368 | 0.80 | EPHX1 (0.53) | EPHX1TSHRKMT2AMEN1POLB | |
| SCHEMBL8503544 | 0.79 | BACE1 (0.52) | MAPTTSHRLMNAALDH1A1 | |
| SCHEMBL7902731 | 0.79 | TSHR (0.54) | EPHX1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL7141149 | 0.79 | BACE1 (0.52) | MAPTTSHRLMNAALDH1A1 | |
| SCHEMBL8856846 | 0.79 | BACE1 (0.52) | MAPTTSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153692-B1 | METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4621150-A | METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0153692-A2 | Method for isomerization a glycidate derivative | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1985-09-04 | — | — | EP | disclosed |