Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 3/20 | 0.40 |
| ▸ | RUNX1 | Q01196 | 6/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527662 | 0.92 | RUNX1 (0.33) | CBFBRUNX1 | |
| SCHEMBL9527362 | 0.91 | ATP4A (0.40) | CBFBRUNX1PDE2ATRPV1 | |
| SCHEMBL9527256 | 0.91 | CBFB (0.34) | CBFBRUNX1 | |
| SCHEMBL9526251 | 0.89 | ATP4A (0.38) | PDE10ATRPV1 | |
| SCHEMBL9528109 | 0.88 | CYP3A4 (0.40) | CBFB | |
| SCHEMBL9526905 | 0.86 | CBFB (0.35) | CBFBRUNX1PDE10ATRPV1PTGS1 | |
| SCHEMBL10713063 | 0.85 | KIF11 (0.39) | CBFBPDE10APDE2ATRPV1 | |
| SCHEMBL23988513 | 0.83 | ATP4A (0.45) | CBFBRUNX1 | |
| SCHEMBL9527817 | 0.83 | ATP4A (0.36) | CBFBRUNX1PDE10A | |
| SCHEMBL9527017 | 0.83 | ATP4A (0.45) | CBFBRUNX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134400-B1 | FLUOROALKOXYSUBSTITUTED PYRIDYLMETHYLTHIO-(OR SULFINYL-)BENZIMIDAZOLES HAVING A SECRETOLYTIC ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-4555518-A | ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1985-11-26 | — | — | US | disclosed |
| EP-0134400-A2 | Fluoroalkoxysubstituted pyridylmethylthio-(or sulfinyl-)benzimidazoles having a secretolytic activity | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-03-20 | — | — | EP | disclosed |