Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.84 |
| ▸ | HTR1A | P08908 | 1/20 | 0.84 |
| ▸ | DRD4 | P21917 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925913 | 0.96 | DRD2 (0.90) | DRD2HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL11011731 | 0.95 | DRD2 (0.91) | DRD2HTR1ADRD4 | |
| Tandospirone SCHEMBL4445506 | 0.91 | DRD2 (1.00) | DRD2HTR1ADRD4 | |
| Tandospirone SCHEMBL22693814 | 0.91 | DRD2 (1.00) | DRD2HTR1ADRD4 | |
| Tandospirone SCHEMBL22381099 | 0.91 | DRD2 (1.00) | DRD2HTR1ADRD4 | |
| Tandospirone SCHEMBL49026 | 0.91 | DRD2 (1.00) | DRD2HTR1ADRD4 | |
| Tandospirone SCHEMBL13532602 | 0.91 | DRD2 (1.00) | DRD2HTR1ADRD4 | |
| Tandospirone SCHEMBL16339864 | 0.90 | DRD2 (1.00) | DRD2HTR1ADRD4 | |
| Tandospirone SCHEMBL1766255 | 0.90 | DRD2 (1.00) | DRD2HTR1ADRD4 | |
| SCHEMBL9527056 | 0.87 | DRD2 (0.71) | DRD2HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220873-B1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PROD (US) | 1993-11-24 | — | — | EP | claimed |
| US-4892943-A | ANTIPSYCHOTIC, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-09 | — | — | US | claimed |
| EP-0220873-B1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PROD (US) | 1993-11-24 | — | — | EP | disclosed |
| US-4892943-A | ANTIPSYCHOTIC, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
| EP-0220873-A1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-06 | — | — | EP | disclosed |