Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 9/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 4/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.51 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682356 | 0.85 | NISCH (0.54) | NISCHGAATSHRTOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL11680052 | 0.85 | NISCH (0.57) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL4703726 | 0.85 | NISCH (0.58) | NISCHGAATSHRTOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL11761895 | 0.84 | NISCH (0.53) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL18282371 | 0.80 | NISCH (0.62) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL13327264 | 0.79 | NISCH (0.81) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL1935706 | 0.77 | NISCH (0.55) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL5798100 | 0.77 | NISCH (0.61) | NISCHTOP2ATOP2BPPARGLMNA | |
| SCHEMBL4701782 | 0.76 | NISCH (0.59) | NISCHTOP2ATOP2BPPARGLMNA | |
| SCHEMBL3900295 | 0.75 | NISCH (0.64) | NISCHGAATSHRTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187500-B1 | MONOBACTAMS | THE UPJOHN COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0187500-A1 | Monobactams | THE UPJOHN COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |