Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 8/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | TOP2A | P11388 | 4/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.57 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496851 | 0.90 | NISCH (0.62) | NISCHTOP2ATOP2BLMNARECQL | |
| Hydrochloric Acid SCHEMBL3900407 | 0.88 | NISCH (0.61) | NISCHTOP2ATOP2BLMNARECQL | |
| Hydrochloric Acid SCHEMBL8204973 | 0.87 | NISCH (0.64) | NISCHTOP2ATOP2BLMNARECQL | |
| SCHEMBL13327264 | 0.84 | NISCH (0.81) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL13160509 | 0.81 | FDPS (0.62) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL31238394 | 0.81 | FDPS (0.62) | NISCHGAATSHRTOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL11680052 | 0.78 | NISCH (0.57) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL6365864 | 0.78 | NISCH (1.00) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL5467582 | 0.78 | KDM4E (0.59) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL1935706 | 0.76 | NISCH (0.55) | NISCHGAATSHRTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |