Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.59 |
| ▸ | DRD3 | P35462 | 6/20 | 0.44 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9528130 | 0.98 | DRD2 (0.58) | DRD2DRD3DRD4SIGMAR1SLC6A4 | |
| SCHEMBL2275944 | 0.80 | DRD2 (0.45) | DRD2DRD3DRD4SIGMAR1OPRM1 | |
| SCHEMBL613058 | 0.79 | DRD2 (0.66) | DRD2SIGMAR1SLC6A4SLC6A3OPRM1 | |
| SCHEMBL21964251 | 0.78 | DRD2 (0.41) | DRD2DRD3DRD4SLC6A4SLC6A3 | |
| SCHEMBL16553869 | 0.77 | SLC6A4 (0.49) | DRD2DRD3DRD4SLC6A4SLC6A3 | |
| SCHEMBL23605548 | 0.77 | DRD2 (0.37) | DRD2DRD3DRD4CCR1 | |
| SCHEMBL652586 | 0.76 | DRD2 (0.68) | DRD2DRD3DRD4SIGMAR1OPRM1 | |
| SCHEMBL4702541 | 0.76 | DRD2 (0.45) | DRD2OPRM1OPRK1OPRL1 | |
| SCHEMBL23577531 | 0.76 | GABRD (0.43) | — | |
| SCHEMBL4702871 | 0.75 | DRD2 (0.47) | DRD2SIGMAR1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |