Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 10/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532300 | 0.89 | TBXAS1 (0.57) | TBXAS1TBXA2RRAB9AKMT2ATAAR1 | |
| SCHEMBL9528581 | 0.88 | TBXAS1 (0.59) | TBXAS1TBXA2RRAB9AKMT2ATAAR1 | |
| SCHEMBL9531103 | 0.86 | TBXAS1 (0.50) | TBXAS1TBXA2RRAB9AKMT2ATAAR1 | |
| SCHEMBL9529953 | 0.86 | ALDH1A1 (0.60) | TBXAS1TBXA2RRAB9AKMT2ATAAR1 | |
| SCHEMBL9528734 | 0.85 | TBXA2R (0.72) | TBXAS1TBXA2RCYP11B1CYP11B2 | |
| SCHEMBL9528365 | 0.84 | TBXAS1 (0.58) | TBXAS1TBXA2RKMT2ATAAR1ALDH1A1 | |
| SCHEMBL9528993 | 0.81 | CYP19A1 (0.53) | TBXAS1TBXA2RAGTR1CYP11B1CYP11B2 | |
| SCHEMBL9529178 | 0.81 | ALDH1A1 (0.60) | TBXAS1TBXA2RRAB9AKMT2ATAAR1 | |
| SCHEMBL9527554 | 0.81 | ALDH1A1 (0.61) | TBXAS1TBXA2RKMT2ATAAR1ALDH1A1 | |
| SCHEMBL9527952 | 0.81 | ALDH1A1 (0.49) | TBXAS1TBXA2RRAB9ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |