Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528215 | 1.00 | RARB (0.49) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL3992298 | 0.87 | THRB (0.43) | SMN1; SMN2HSD17B10MEN1KMT2AUSP2 | |
| SCHEMBL8913819 | 0.80 | RARB (0.46) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9525248 | 0.80 | RARB (0.39) | RARBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL9528031 | 0.79 | RARB (0.46) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9528028 | 0.79 | RARB (0.46) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9525985 | 0.78 | PTGES (0.38) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9274067 | 0.78 | RARB (0.47) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9528232 | 0.78 | RARB (0.47) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7506274 | 0.77 | RARB (0.51) | RARBRAB9AMAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351746-B1 | Optically active 1,3-dioxolane derivatives containing a mesogene group in position 4, method for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0351746-A1 | Optically active 1,3-dioxolane derivatives containing a mesogene group in position 4, method for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-24 | — | — | EP | disclosed |