Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 8/20 | 0.67 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9531575 | 0.99 | CCKBR (0.66) | CCKBROPRD1OPRK1LMNAOPRM1 | |
| SCHEMBL9499814 | 0.86 | CCKBR (0.73) | CCKBROPRD1OPRK1OPRM1 | |
| Water SCHEMBL9500311 | 0.86 | CCKBR (0.55) | CCKBRLMNA | |
| Hydrochloric Acid SCHEMBL9499318 | 0.86 | CCKBR (0.72) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL9501387 | 0.81 | CCKBR (1.00) | CCKBROPRD1OPRK1 | |
| SCHEMBL9499716 | 0.80 | CCKBR (1.00) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL9501463 | 0.78 | LMNA (0.52) | CCKBRLMNA | |
| SCHEMBL9528589 | 0.78 | CCKBR (0.53) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL10803682 | 0.77 | CCKBR (0.75) | CCKBROPRD1OPRK1OPRM1 | |
| Water SCHEMBL9531569 | 0.77 | CCKBR (0.52) | CCKBROPRD1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166356-B1 | 2-SUBSTITUTED-AMINOMETHYL-1,4-BENZODIAZEPINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1993-09-01 | — | — | EP | claimed |
| US-4724237-A | GASTROINTESTINAL, CENTRAL NERVOUS, AND APPETITE DISORDERS | MERCK & CO., INC. (US) | 1988-02-09 | — | — | US | claimed |
| EP-0166356-A2 | 2-Substituted-aminomethyl-1,4-benzodiazepines, process for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-01-02 | — | — | EP | claimed |
| EP-0166356-B1 | 2-SUBSTITUTED-AMINOMETHYL-1,4-BENZODIAZEPINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1993-09-01 | — | — | EP | disclosed |