SCHEMBL9528664

SCHEMBL9528664

Cc1ccc(CCON=C(c2ccccc2)c2cccnc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 12/20 0.60
ALDH1A1 P00352 4/20 0.59
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
TBXA2R P21731 11/20 0.48
TAAR1 Q96RJ0 1/20 0.45
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9527554 0.96 ALDH1A1 (0.61) TBXAS1ALDH1A1KMT2AMEN1MAPT
SCHEMBL9528581 0.91 TBXAS1 (0.59) TBXAS1ALDH1A1KMT2AMEN1MAPT
SCHEMBL9532300 0.90 TBXAS1 (0.57) TBXAS1ALDH1A1KMT2AMEN1TBXA2R
SCHEMBL9532138 0.88 TBXAS1 (0.55) TBXAS1ALDH1A1KMT2AMEN1MAPT
SCHEMBL9530136 0.87 ALDH1A1 (0.62) TBXAS1ALDH1A1KMT2AMEN1MAPT
SCHEMBL9528365 0.87 TBXAS1 (0.58) TBXAS1ALDH1A1KMT2AMEN1MAPT
SCHEMBL9529953 0.87 ALDH1A1 (0.60) TBXAS1ALDH1A1KMT2AMEN1MAPT
SCHEMBL9529178 0.87 ALDH1A1 (0.60) TBXAS1ALDH1A1KMT2AMEN1MAPT
SCHEMBL9529664 0.83 TBXAS1 (0.63) TBXAS1ALDH1A1KMT2ATBXA2RKDM4E
SCHEMBL9527676 0.83 TBXAS1 (0.63) TBXAS1ALDH1A1KMT2ATBXA2RKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0366006-B1 PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT KAKEN PHARMACEUTICAL CO., LTD. (JP) 1993-09-29 EP disclosed
EP-0366006-A1 Pyridylketoxime ether compound and pharmaceutical composition containing it KAKEN PHARMACEUTICAL CO., LTD. (JP) 1990-05-02 EP disclosed