Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.60 |
| ▸ | GABRD | O14764 | 4/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.60 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.60 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.60 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.60 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.60 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.60 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.60 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.60 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.60 |
| ▸ | GABRE | P78334 | 4/20 | 0.60 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.60 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.60 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.60 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4004689 | 0.80 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19857498 | 0.77 | GABRP (0.66) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL20033622 | 0.77 | GABRP (0.66) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13611417 | 0.76 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2859500 | 0.75 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4176344 | 0.74 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28933112 | 0.74 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28571365 | 0.74 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27351041 | 0.73 | NOS3 (0.36) | SMN1; SMN2 | |
| SCHEMBL16421183 | 0.71 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394476-B1 | NOVEL 1,3,4-THIADIAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1993-07-28 | — | — | EP | claimed |