Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528738 | 1.00 | PLA2G2A (0.37) | PLA2G2APLA2G10PLA2G1BPLA2G5PTGES | |
| SCHEMBL9532381 | 0.87 | PLA2G2A (0.38) | PLA2G2APLA2G10PLA2G1BPLA2G5PTGES | |
| SCHEMBL9532388 | 0.87 | PLA2G2A (0.38) | PLA2G2APLA2G10PLA2G1BPLA2G5PTGES | |
| SCHEMBL9528861 | 0.84 | PPARA (0.31) | PLA2G2A | |
| SCHEMBL9532313 | 0.79 | PPARA (0.36) | PLA2G2APTGESALOX5PPARG | |
| SCHEMBL9529384 | 0.75 | PLA2G2A (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9529381 | 0.75 | PLA2G2A (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9531869 | 0.73 | PPARA (0.39) | PLA2G2A | |
| SCHEMBL9531863 | 0.73 | PPARA (0.39) | PLA2G2A | |
| SCHEMBL10770807 | 0.69 | PPARA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |