Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 12/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529381 | 1.00 | PLA2G2A (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5SMPD1 | |
| SCHEMBL9532388 | 0.83 | PLA2G2A (0.38) | PLA2G2APLA2G10PLA2G1BPLA2G5PPARA | |
| SCHEMBL9528797 | 0.83 | PLA2G2A (0.37) | PLA2G2APLA2G10PLA2G1BPLA2G5SMPD1 | |
| SCHEMBL10770807 | 0.79 | PPARA (0.38) | SMPD1PPARATDP1NPC1RXFP1 | |
| SCHEMBL9532313 | 0.77 | PPARA (0.36) | PLA2G2ASMPD1PPARANPC1 | |
| SCHEMBL9529484 | 0.77 | SMPD1 (0.34) | PLA2G2ASMPD1PPARA | |
| SCHEMBL9532063 | 0.76 | PPARA (0.41) | PLA2G2ASMPD1PPARACNR2 | |
| SCHEMBL9532070 | 0.76 | PPARA (0.41) | PLA2G2ASMPD1PPARACNR2 | |
| SCHEMBL9798976 | 0.76 | ALDH1A1 (0.41) | SMPD1PPARATDP1NPC1 | |
| SCHEMBL9528738 | 0.75 | PLA2G2A (0.37) | PLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |