Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528808 | 0.85 | EPHX1 (0.52) | NOS3NOS1EPHX1NPC1RAB9A | |
| SCHEMBL10453854 | 0.85 | EPHX1 (0.52) | NOS3NOS1EPHX1NPC1RAB9A | |
| SCHEMBL9529338 | 0.85 | EPHX1 (0.52) | NOS3NOS1EPHX1NPC1RAB9A | |
| SCHEMBL10453587 | 0.85 | EPHX1 (0.52) | NOS3NOS1EPHX1NPC1RAB9A | |
| SCHEMBL10453586 | 0.85 | EPHX1 (0.52) | NOS3NOS1EPHX1NPC1RAB9A | |
| SCHEMBL9528814 | 0.85 | EPHX1 (0.52) | NOS3NOS1EPHX1NPC1RAB9A | |
| SCHEMBL10453853 | 0.85 | EPHX1 (0.52) | NOS3NOS1EPHX1NPC1RAB9A | |
| SCHEMBL9529332 | 0.85 | EPHX1 (0.52) | NOS3NOS1EPHX1NPC1RAB9A | |
| SCHEMBL9529412 | 0.78 | HSD17B10 (0.40) | NOS3NOS1NPC1RAB9AHTT | |
| SCHEMBL9529169 | 0.76 | IDO1 (0.47) | NOS3NOS1EPHX1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |