Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528763 | 0.78 | NOS3 (0.40) | NOS3NOS1EPHX2MAPTSMN1; SMN2 | |
| SCHEMBL10453587 | 0.76 | EPHX1 (0.52) | HSD17B10NOS3NOS1EPHX2MAPT | |
| SCHEMBL9528808 | 0.76 | EPHX1 (0.52) | HSD17B10NOS3NOS1EPHX2MAPT | |
| SCHEMBL10453854 | 0.76 | EPHX1 (0.52) | HSD17B10NOS3NOS1EPHX2MAPT | |
| SCHEMBL10453586 | 0.76 | EPHX1 (0.52) | HSD17B10NOS3NOS1EPHX2MAPT | |
| SCHEMBL9529332 | 0.76 | EPHX1 (0.52) | HSD17B10NOS3NOS1EPHX2MAPT | |
| SCHEMBL9529338 | 0.76 | EPHX1 (0.52) | HSD17B10NOS3NOS1EPHX2MAPT | |
| SCHEMBL9528814 | 0.76 | EPHX1 (0.52) | HSD17B10NOS3NOS1EPHX2MAPT | |
| SCHEMBL10453853 | 0.76 | EPHX1 (0.52) | HSD17B10NOS3NOS1EPHX2MAPT | |
| SCHEMBL945076 | 0.75 | MAPT (0.44) | HSD17B10EPHX2MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |