Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 4/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 4/20 | 0.39 |
| ▸ | GBA1 | P04062 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528773 | 1.00 | L3MBTL1 (0.40) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL25875655 | 0.86 | L3MBTL1 (0.47) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL10687180 | 0.84 | KMT2A (0.38) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL10848462 | 0.80 | LMNA (0.49) | CA1CA2CA7CA9 | |
| SCHEMBL16826139 | 0.80 | UGCG (0.48) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL28990361 | 0.80 | UGCG (0.48) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL8607233 | 0.80 | UGCG (0.48) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL8878661 | 0.78 | TSHR (0.47) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL9530591 | 0.78 | LMNA (0.41) | KMT2AHTT | |
| SCHEMBL8814209 | 0.77 | CA1 (0.45) | CA1CA2CA7CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251827-B1 | NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |