Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | P2RY10 | O00398 | 6/20 | 0.35 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798498 | 0.85 | PLA2G2C (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL9527787 | 0.79 | PLA2G4A (0.35) | PLA2G2CP2RY10SMPD1 | |
| SCHEMBL9531999 | 0.79 | PLA2G4A (0.33) | PLA2G2APLA2G2CP2RY10SMPD1 | |
| SCHEMBL9529484 | 0.79 | SMPD1 (0.34) | PLA2G2APLA2G2CP2RY10GPR34SMPD1 | |
| SCHEMBL10646794 | 0.77 | PLA2G2C (0.45) | PLA2G2CP2RY10LPAR1LPAR3 | |
| SCHEMBL9529973 | 0.76 | SOAT1 (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9529975 | 0.76 | SOAT1 (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10832029 | 0.76 | PLA2G2C (0.43) | PLA2G2CP2RY10GPR34GPR174LPAR1 | |
| SCHEMBL10937660 | 0.75 | PLA2G4A (0.42) | PLA2G2APLA2G2CP2RY10LPAR1LPAR3 | |
| SCHEMBL10933383 | 0.75 | P2RY10 (0.42) | PLA2G2CP2RY10GPR34LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |