Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | P2RY10 | O00398 | 5/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.33 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527787 | 0.88 | PLA2G4A (0.35) | SMPD1P2RY10PLA2G2CPLA2G4APPARA | |
| SCHEMBL9531999 | 0.87 | PLA2G4A (0.33) | SMPD1P2RY10PLA2G2APLA2G2CPLA2G4A | |
| SCHEMBL9528797 | 0.86 | PLA2G2A (0.37) | SMPD1PLA2G2APLA2G2CPLA2G4APPARA | |
| SCHEMBL9529222 | 0.82 | ALDH1A1 (0.38) | PPARA | |
| Bromide SCHEMBL9528346 | 0.81 | ALDH1A1 (0.38) | PPARA | |
| SCHEMBL9528884 | 0.79 | PLA2G2A (0.37) | SMPD1P2RY10PLA2G2AGPR34PLA2G2C | |
| SCHEMBL9799024 | 0.77 | SMPD1 (0.35) | SMPD1P2RY10PLA2G2AGPR34PLA2G2C | |
| SCHEMBL9529381 | 0.77 | PLA2G2A (0.41) | SMPD1PLA2G2APPARA | |
| SCHEMBL10718796 | 0.70 | PLA2G2C (0.42) | P2RY10PLA2G2AGPR34PLA2G2C | |
| SCHEMBL10933383 | 0.70 | P2RY10 (0.42) | P2RY10GPR34PLA2G2CADKS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | claimed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | claimed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | claimed |
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |