Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274807 | 0.86 | TACR1 (0.61) | TACR1TACR3MEN1KMT2A | |
| SCHEMBL8485370 | 0.86 | TACR1 (0.61) | TACR1TACR3MEN1KMT2A | |
| SCHEMBL8486077 | 0.84 | CCKBR (0.61) | MEN1KMT2AMAPTCCKBR | |
| SCHEMBL9373898 | 0.82 | TACR1 (0.51) | TACR1TACR3MEN1KMT2AMAPT | |
| SCHEMBL6888854 | 0.82 | TACR1 (0.46) | TACR1TACR3MEN1KMT2AADRB3 | |
| SCHEMBL9083862 | 0.80 | TACR1 (0.56) | TACR1TACR3CCKBR | |
| SCHEMBL9539016 | 0.80 | CCKAR (0.48) | CCKBR | |
| SCHEMBL9539010 | 0.80 | CCKAR (0.48) | CCKBR | |
| SCHEMBL6888466 | 0.79 | USP2 (0.47) | TACR1MEN1KMT2AMAPTACE | |
| SCHEMBL8701934 | 0.78 | KMT2A (0.40) | MEN1KMT2AMAPTCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546123-A1 | ALPHA-SUBSTITUTED TRYPTOPHANE DIPEPTOID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992004322-A1 | ALPHA-SUBSTITUTED TRYPTOPHANE DIPEPTOID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |