Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CCKBR | P32239 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894334 | 0.81 | CCKBR (0.51) | CCKBR | |
| SCHEMBL8486077 | 0.79 | CCKBR (0.61) | KMT2AMEN1LMNACYP1A2PKM | |
| SCHEMBL9528893 | 0.78 | TACR1 (0.47) | KMT2AMEN1MAPTCCKBR | |
| SCHEMBL9376780 | 0.74 | NMBR (0.60) | ALDH1A1 | |
| SCHEMBL8485370 | 0.74 | TACR1 (0.61) | KMT2AMEN1 | |
| SCHEMBL9274807 | 0.74 | TACR1 (0.61) | KMT2AMEN1 | |
| SCHEMBL9373898 | 0.73 | TACR1 (0.51) | KMT2AMEN1TSHRMAPTALDH1A1 | |
| SCHEMBL8829902 | 0.73 | ALDH1A1 (0.55) | KMT2AMEN1LMNACYP1A2PKM | |
| SCHEMBL9373877 | 0.72 | NMBR (0.59) | — | |
| SCHEMBL8488187 | 0.72 | NMBR (0.50) | KMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846942-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1998-12-08 | — | — | US | disclosed |