Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 3/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1543223 | 0.84 | CYP3A4 (0.47) | L3MBTL1CYP1A1KMT2AKDM4EMAPT | |
| SCHEMBL1543134 | 0.82 | CYP1A1 (0.42) | L3MBTL1CYP1A1KMT2AKDM4EMAPT | |
| SCHEMBL2128081 | 0.81 | RARA (0.42) | L3MBTL1CYP1A1BRD4CREBBPPDGFRB | |
| SCHEMBL30452106 | 0.77 | KDM4E (0.57) | L3MBTL1KMT2APDE4AKDM4ESMN1; SMN2 | |
| SCHEMBL28179454 | 0.76 | KDM4E (0.53) | L3MBTL1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL1542685 | 0.76 | CYP3A4 (0.55) | CYP1A1BRD4KDRPDGFRB | |
| SCHEMBL9141285 | 0.75 | KMT2A (0.55) | L3MBTL1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL5478760 | 0.73 | PTPRC (0.61) | L3MBTL1KMT2APDE4AKDM4ESMN1; SMN2 | |
| SCHEMBL10567524 | 0.73 | ALDH1A1 (0.62) | L3MBTL1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL215300 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |