Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | HTT | P42858 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5946453 | 0.82 | MAPT (0.77) | RECQLMAPTALDH1A1HTTHPGD | |
| SCHEMBL29176317 | 0.81 | RECQL (1.00) | RECQLMAPTALDH1A1HTTHPGD | |
| SCHEMBL425338 | 0.81 | RECQL (1.00) | RECQLMAPTALDH1A1HTTHPGD | |
| SCHEMBL446006 | 0.81 | RECQL (1.00) | RECQLMAPTALDH1A1HTTHPGD | |
| SCHEMBL5800440 | 0.80 | RECQL (0.71) | RECQLMAPTALDH1A1HTTHPGD | |
| SCHEMBL22449502 | 0.80 | RECQL (0.71) | RECQLMAPTALDH1A1HTTHPGD | |
| SCHEMBL12685619 | 0.78 | MAPT (0.67) | RECQLMAPTALDH1A1HTTHPGD | |
| SCHEMBL1449217 | 0.77 | RECQL (0.66) | RECQLMAPTALDH1A1HTTHPGD | |
| SCHEMBL14063274 | 0.77 | RECQL (0.66) | RECQLMAPTALDH1A1HTTHPGD | |
| SCHEMBL12742903 | 0.77 | RECQL (0.66) | RECQLMAPTALDH1A1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |