Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 5/20 | 0.51 |
| ▸ | ESRRB | O95718 | 2/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563816 | 0.83 | L3MBTL1 (0.49) | NLRP3EPHX2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9532375 | 0.79 | ALDH1A1 (0.50) | EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9531767 | 0.78 | GAA (0.51) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9529403 | 0.78 | MEN1 (0.50) | NLRP3ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9527224 | 0.77 | HTT (0.60) | NLRP3ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11847434 | 0.77 | NR1H4 (0.46) | ESRRGESRRBNLRP3NR1H4EPHX2 | |
| SCHEMBL11510766 | 0.75 | NR1H4 (0.47) | ESRRGESRRBNR1H4EPHX2ALDH1A1 | |
| SCHEMBL840854 | 0.75 | NR1H4 (0.70) | NR1H4EPHX2ALDH1A1LMNAMAPT | |
| SCHEMBL4104911 | 0.75 | ESRRG (0.67) | ESRRGESRRBNR1H4EPHX2LMNA | |
| Hydrochloric Acid SCHEMBL2528372 | 0.73 | NR1H4 (0.68) | NR1H4EPHX2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | claimed |
| EP-0252474-B1 | HYDRAZINE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
| EP-0525832-A1 | Substituted 1,2,3- thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4803280-A | Substituted 1,2,3-thia-diazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0252474-A2 | Hydrazine derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |