Acetone

Acetone

SCHEMBL9529315

CC(C)=O.CC1CCCCC1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 0.50
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
KMT2A Q03164 1/20 0.40
RECQL P46063 1/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP3A4 P08684 1/20 0.38
EPHX2 P34913 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL938460 0.91 EPHX1 (0.48) EPHX1CES2CES1KMT2ARECQL
Acetic Acid SCHEMBL4093239 0.91 EPHX1 (0.48) EPHX1CES2CES1KMT2ARECQL
Acetic Acid SCHEMBL4087167 0.91 EPHX1 (0.48) EPHX1CES2CES1KMT2ARECQL
Bicarbonate SCHEMBL17847302 0.88 EPHX1 (0.50) EPHX1CES2CES1KMT2ARECQL
Methylcyclopentane SCHEMBL4087874 0.88 EPHX1 (0.44) EPHX1CES2CES1KMT2ARECQL
Bicarbonate SCHEMBL4695324 0.88 EPHX1 (0.50) EPHX1CES2CES1KMT2ARECQL
Bicarbonate SCHEMBL8913592 0.88 EPHX1 (0.50) EPHX1CES2CES1KMT2ARECQL
Methylcyclopentane SCHEMBL4362497 0.88 EPHX1 (0.44) EPHX1CES2CES1KMT2ARECQL
Acetone SCHEMBL594272 0.87
Hexane SCHEMBL16835583 0.85 NAAA (0.47) EPHX1KMT2AMAPTEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105254843-B Polyisocyantates composition, blocked polyisocyanates composition and their manufacturing method 旭化成株式会社 2019-08-06 CN disclosed
CN-109790277-A Polyisocyantates composition, blocked polyisocyanates composition, application composition, aqueous coating composition and coating substrate 旭化成株式会社 2019-05-21 CN disclosed
CN-105339408-B Polyisocyanate composition and method for producing same, blocked polyisocyanate composition and method for producing same, resin composition, curable resin composition, and cured product 旭化成株式会社 2018-09-21 CN disclosed
CN-107922584-A Blocked polyisocyanates composition, one-pack-type application composition, film and coated article 旭化成株式会社 2018-04-17 CN disclosed
EP-2709993-A2 AMORPHOUS MIRABEGRON AND PROCESSES FOR CRYSTAL FORMS OF MIRABEGRON Dr. Reddy's Laboratories Ltd. (IN) 2014-03-26 EP disclosed
WO-2012156998-A2 AMORPHOUS MIRABEGRON AND PROCESSES FOR CRYSTAL FORMS OF MIRABEGRON DR. REDDY'S LABORATORIES LIMITED (IN) 2012-11-22 WO disclosed
EP-0252474-B1 HYDRAZINE DERIVATIVES AMERICAN CYANAMID COMPANY (US) 1993-04-21 EP disclosed
EP-0525832-A1 Substituted 1,2,3- thiadiazole-4-thiolates AMERICAN CYANAMID COMPANY (US) 1993-02-03 EP disclosed
US-4916237-A Substituted 1,2,3-thiadiazole-4-thiolates AMERICAN CYANAMID COMPANY (US) 1990-04-10 US disclosed
US-4803280-A Substituted 1,2,3-thia-diazole-4-thiolates AMERICAN CYANAMID COMPANY (US) 1989-02-07 US disclosed
EP-0252474-A2 Hydrazine derivatives AMERICAN CYANAMID COMPANY (US) 1988-01-13 EP disclosed