Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 12/20 | 0.46 |
| ▸ | CA9 | Q16790 | 9/20 | 0.46 |
| ▸ | CA1 | P00915 | 9/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779427 | 0.82 | SOS1 (0.48) | SOS1CA2CA9CA1CA12 | |
| SCHEMBL31634374 | 0.80 | SOS1 (0.47) | SOS1CA2CA9CA1CA12 | |
| SCHEMBL4348245 | 0.80 | CA2 (0.64) | CA2CA9CA1CA12ENPP1 | |
| SCHEMBL16140142 | 0.80 | SOS1 (0.47) | SOS1CA2CA9CA1CA12 | |
| SCHEMBL3736307 | 0.78 | SOS1 (0.45) | SOS1CA2CA9CA1CA12 | |
| SCHEMBL9451266 | 0.78 | CA2 (0.76) | SOS1CA2CA9CA1CA12 | |
| SCHEMBL4822537 | 0.78 | CA1 (0.61) | CA2CA9CA1CA12CA7 | |
| SCHEMBL1941544 | 0.78 | CA2 (0.61) | CA2CA9CA1CA12TEAD4 | |
| SCHEMBL14015383 | 0.78 | CA2 (0.49) | SOS1CA2CA9CA1CA12 | |
| SCHEMBL9788649 | 0.78 | CA2 (0.61) | CA2CA9CA1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270947-B1 | SUBSTITUTED BASIC 2-AMINOTETRALINES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0270947-A2 | Substituted basic 2-aminotetralines | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| EP-0010249-A2 | Herbicidal agents, process for their preparation and their use in combating weeds | BAYER AG (DE) | 1980-04-30 | — | — | EP | disclosed |
| EP-0010250-A2 | Use of Sulfonanilides in inhibition of plant growth | BAYER AG (DE) | 1980-04-30 | — | — | EP | disclosed |