Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.50 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.50 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273196 | 0.85 | HPGD (0.64) | KMT2AALDH1A1HPGDGFERCYP2C19 | |
| SCHEMBL27961040 | 0.85 | HPGD (0.64) | KMT2AALDH1A1HPGDGFERCYP2C19 | |
| SCHEMBL18228579 | 0.84 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1GFERCYP3A4 | |
| SCHEMBL18239363 | 0.84 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1GFERCYP3A4 | |
| SCHEMBL28341134 | 0.83 | HPGD (0.68) | KMT2AALDH1A1HPGDGFERCYP2C19 | |
| Water SCHEMBL9518556 | 0.83 | HPGD (0.61) | KMT2AALDH1A1HPGDGFERCYP2C19 | |
| SCHEMBL17302028 | 0.82 | KMT2A (0.56) | KMT2AMEN1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL9532153 | 0.81 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1HPGDGFER | |
| SCHEMBL18787394 | 0.80 | KMT2A (0.54) | KMT2AMEN1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL9768858 | 0.80 | KMT2A (0.54) | KMT2AMEN1ALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |
| EP-0136640-A2 | Trichloroacryloyloxime derivatives, process for their preparation and fungicides for agriculture | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-04-10 | — | — | EP | disclosed |
| US-4297359-A | ANTISECRETORY AGENTS; GASTROINTESTINAL DISORDERS | ACF CHEMIEFARMA NV (NL) | 1981-10-27 | — | — | US | disclosed |
| EP-0007679-A1 | Oxime ethers, processes for their manufacture and pharmaceutical compositions thereof | ACF CHEMIEFARMA NV (NL) | 1980-02-06 | — | — | EP | disclosed |